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What is the Endocannabinoid System?
What is the Endocannabinoid System?
The Endocannbinoid System Structure and Function
The Endocannbinoid System Structure and Function
The endocannabinoid system (ECS) plays a critical role in our survival. This is due to its ability to maintain homeostasis (balance) of the human body, which encompasses the brain, endocrine, and immune system. It is present nearly everywhere in the human body; ECS is a unique system in multiple dimensions.
To begin with, it is a retrograde system functioning post- to pre-synapse, allowing it to be a “master regulator” in the body. Secondly, it has a very wide scope of influence due to an abundance of cannabinoid receptors located everywhere from immune cells to neurons. Finally, cannabinoids are rapidly synthesized and degraded, so they do not stay in the body for very long in high amounts, possibly enabling cannabinoid therapy to be a safer alternative to opioids or benzodiazepines.
Multiple known endocannabinoids effect the ECS. All of them seem to have a purpose in anti-proliferative, anti-inflammatory, and anti-metastatic effects (Madia & Daeninck, 2016). Additionally, it appears that they have a role in neurotransmitter, immune system, and mitochondrial function. The mitochondria are responsible for converting carbohydrates and fatty acids into adenosine triphosphate (ATP) and providing energy for cells.
The Endocannabinoid System is Our Universal Regulator
We are hard-wired with a system of cannabinoid receptors throughout our brains and bodies. When these receptors are activated, they enable two-way communication between body systems; something previously thought to be impossible. So what does it mean to literally have a cannabinoid system inside the body? It means that we were designed to regularly supply our ECS with the nutrients it was designed for, in support of vital communications between the control centers of the body and every other system. When this system is out of balance, we experience distress.
Full Spectrum Products
Full Spectrum Products
Full Spectrum means the maximum amount of helpful native phytochemicals are retained during extraction. The goal is to remove extraneous lipids while retaining an identical ratio of cannabinoids, terpenes, and flavonoids from the original plant source material. This is verified by testing the material before and after the extraction. True Full Spectrum extracts are rarer than one might expect; most extractions lose significant terpenes and flavonoids during processing because they are much more volatile than cannabinoids. Full Spectrum extracts tend to be quite dark in color, and their flavor is often described as natural and earthy. We have chosen a full spectrum extraction process to ensure we capture of all of the hemp plant properties, and we add hops oil (BCP).
*Our certificates of analysis are available on the products information page.
Today’s consumers are becoming more curious about which CBD options work best for them and why. The ECS is as unique as a fingerprint; everyone is different, and trial and error is inherent in the journey toward optimization. However, the chemicals produced in the plant alongside cannabinoids have more predictable and well-studied effects than the cannabinoids themselves. Knowing the phytochemical profile of a hemp or cannabis extract can help developers define and standardize their products at scale.
Hemp-derived Cannabinoid
CBD
Hemp-derived Cannabinoid
CBD
CBD, also known as Cannabidiol, is the non-psychoactive component of the cannabis-stavia (Hemp) plant and was labelled as having no public health risk or abuse potential by the World Health Organization (WHO) in 2017.
Scientists have identified close to 500 phytochemicals in hemp plants. Hundreds of them are terpenoids, which are the compounds that give fruits, flowers and herbs many of their desirable aromas, flavors and other special properties. Cannabinoids are a sub-class of terpenoids.
There are over 60 cannabinoids found in hemp and cannabis — the only place they are found. This is one of the many reasons hemp stands alone in the plant kingdom as a treasure chest of nutrition without equal.
Imagine a large orchestra, and the members being made to play their instruments while blind-folded. They can’t see the conductor and they can’t read the music. Sometimes they get it right, but most of the time it’s a mess. This is your body without the nutrients provided by hemp. Bringing the body back into harmony could be as simple as replacing this lost nutrition.
Every major civilization in history has recognized hemp as #1 on its list of important plants. The ancient Chinese, Indians, Egyptians, Assyrians, Persians, Greeks and Romans all revered hemp as an incomparable source of food and medicine. Now modern science is validating what the ancients all knew — and uncovering exciting new discoveries about hemp and the Endocannabinoid System.
Hops-derived Terpene
BCP
Hops-derived Terpene
BCP
Beta-Caryophyllene, or BCP, is a terpene (chemical compound) found in medicinal and food plants such as hemp, black pepper, clove oil, hops, oregano, rosemary, and cinnamon. BCP’s most distinguishing characteristic is that it can be categorized as both a cannabinoid and a terpene. It has been proven to have powerful antimicrobial, antibacterial and anti-inflammatory properties. Similar to CBD, it binds to the brain's CB2 receptors to provide powerful therapeutic relief for chronic pain and inflammation.
This special component of the cannabis plant was first discovered in 1964 by pioneering Israeli academic researcher Raphael Mechoulam, who identified it as a terpene. It wasn’t until 2008 that a study by a group of German scientists observed the rare behavior and characteristics that indicated that BCP can also be labeled a cannabinoid. BCP may enhance the effectiveness of CBD. It’s a natural substance found in many plants and approved by the FDA as safe and effective for some conditions. Studies show that BCP can also help reduce anxiety, depression and other mental conditions. Preclinical studies show that BCP has these inhibitory effects on: pain, inflammation, anxiety, dementia, Parkinson's disease, cancer, neurodegeneration, osteoporosis, endometriosis, epilepsy. Many clients get benefits from BCP alone or in combination with CBD.
CBG
Cannabigerol
Cannabigerol
CBG is a type of cannabinoid obtained from the cannabis/hemp plant. It's often referred to as the mother of all cannabinoids. It is a precursor to activate the ECS. CBG is being considered as a new treatment option for those with Glaucoma due to its ability to reduce intra-ocular pressure. CBG has powerful neuroprotective attributes and vasodilating abilities. This gives CBG the possibility of treating several different eye and degenerative diseases.
CBN
Cannabinol
Cannabinol
CBN was first discovered nearly a century ago. In more ways than one, CBN is something of a “sleeper” cannabinoid. It has a sedative quality that sets it apart from other cannabinoids. The CBN cannabinoid hasn't been researched nearly as rigorously as CBD, THC, or even some terpenes. Yet, according to an analysis from Steep Hill Labs, 5 mg of CBN is as effective as 10-mg of diazepam, a prominent pharmaceutical sedative, anti-insomnia medicine.
CBC
Cannabinchromenes
Cannabinchromenes
CBC like other Cannabinoids works by interacting with your endocannabinoid receptors. One interesting thing about CBC is it does not bind well with the CB1 receptors like many cannabinoids, instead it interacts with receptors responsible for activating pain and inflammation in the body. The key to understanding CBC therapeutic values lies in its ability to connect different nerve channels and change the message being sent by the brain to the body.